To the reader,

When we began this journey a few years ago, we never imagined how deeply it would shape our understanding of ourselves, how the world operates, and the future we wish to create.

This manifesto has been written, deconstructed, and rewritten countless times as we refined our guiding ethos; “Biology and data, at scale, has the power to fully eradicate disease, not just manage symptoms.”

We hope it captures our unwavering belief in the potential of biological data and AI to shape a world free from disease.

Enjoy

(Part 1/3) An entropic world fuels disease

The foundation of life is in every breath we take. Yet, for millions with asthma, chronic sinusitis, and COPD, breathing is a daily battle.

Our world is becoming increasingly entropic and as it evolves, respiratory diseases thrive as a result of:

• Climate change: Causes 4.2M deaths/year linked to pollution and rising temperatures; asthma worsened by 20% longer pollen seasons.
• Wildfires: Raises hospitalizations by 10%, with wildfire frequency increasing 20% globally.
• Urbanization & travel: Spreads pathogens faster with 56% of people in cities and 1.5B trips/year.
• Smoking: Causes 8M deaths/year, including 2.4M respiratory related deaths.
• Chronic disease: Increases respiratory risks due to increases in obesity (200%) and diabetes (400%).

These forces compound to create the perfect storm for more disease, more decay and more deaths.

The question is, how do we stop it?

(Part 2/3) Absolute truths bring order; biology is one of them

Respiratory clinicians often rely on trial-and-error treatments, failing between 30-50% of the time. Diagnostics based on symptoms and imaging reveal little about the root causes, leaving patients in cycles of ineffective therapy and prolonged suffering.